# GSE7880 - R2 (SPMA, matrix, SNR, 3UTR, highest.magnitude, D3, BH, 5)

#### krismer@mit.edu

#### 2018-06-01

# 1 Metadata

## 1.1 Configuration

Analysis approach:

    approach <- "matrix"

Species:

    species <- "human"

Graphical output format:

    graphics.format <- "SVG"

Sequence region:

    sequence.type <- "3UTR"

Number of bins:

    n.bins <- 40

Merge method for duplicate entries:

    merge.method <- "highest.magnitude"

Maximum degree of polynomial model for spectrum evaluation:

    max.model.degree <- 3

P-value adjustment method:

    p.adjust.method <- "BH"

Maxmimum number of binding sites per transcript:

    max.hits <- 5

Motif database:

    motif.db <- "transite"

## 1.2 Sequence data retrieval

- merge rows with duplicate RefSeq identifiers
- retrieve requested sequence regions (3’ UTRs, 5’ UTRs, or mature mRNAs) for each RefSeq identifier using
  - GRCh38/hg38 genome assembly for human platforms
  - GRCm38/mm10 genome assembly for mouse platforms
- draw histogram of length distribution of retrieved sequences
- draw histogram of value distribution of retrieved sequences (“value” column in uploaded file)

The latest genome assembly releases (GRCh38/hg38 for human platforms, GRCm38/mm10 for mouse platforms) are used to retrieve the requested sequence regions for all specified transcripts.

### 1.2.1 Duplicate RefSeq identifier

Number of occurrences per category before merge step:

### 1.2.2 Summary of sequence data

Sequence data retrieval summary:

Property | Value
--- | ---
number of valid RefSeq identifiers | 8472
number of invalid RefSeq identifiers | 73
number of RefSeq identifiers with associated sequence | 8249
species | human
sequence type | 3UTR
platform | custom

Length distribution of retrieved sequences:

### 1.2.3 Value distribution of transcripts

Histogram of the differential expression values (`value` column):

# 2 Matrix-based Spectrum Motif Analysis

Warning: The presented results are speculative and should be used with caution. Especially the link between the RNA-binding protein and its sequence motif (i.e., the PWM) is not well established. It is recommended to interpret the results with the underlying PWMs in mind, instead of only looking at the associated RNA-binding proteins. Sequence motif logos and PWMs of all RNA-binding proteins in the database can be found in the Motif Database section of the Transite website.

Transcripts in bin 1 have smallest value in `value` column, transcripts in bin 40 have greatest value in `value` column.

Binning scheme: 39 bins with 206 transcripts each, last bin with 215 transcripts

## 2.1 Summary

Spectrums that meet the following criteria are considered non-random (and random otherwise):

- adjusted \(R^2 \geq 0.4\)
- local consistency score Monte Carlo sampling \(n > 1000000\)
- at least 10% of bins with significant (\(\alpha = 0.05\)) enrichment or depletion of putative binding sites

Color legend:

spectrum classification: non-random (3 out of 3 criteria met)

spectrum classification: random (2 out of 3 criteria met)

spectrum classification: random (1 out of 3 criteria met)

spectrum classification: random (0 out of 3 criteria met)

Column | Description
--- | ---
ID | unique motif ID
RBPs | RNA-binding proteins associated with this motif
ARS | adjusted \(R^2\)
slope | either slope (if degree 1 polynomial), or coefficient of the linear term (if degree greater than 1); positive slope implies enrichment of putative binding sites in highly ranked transcripts (according to value column), negative slope implies depletion
degree | polynomial degree
p-value | adjusted p-value of local consistency score
* | number of bins with significant (\(\alpha = 0.05\)) enrichment or depletion of putative binding sites
** | number of bins with highly significant (\(\alpha = 0.01\)) enrichment or depletion of putative binding sites
*** | number of bins with extremely significant (\(\alpha = 0.001\)) enrichment or depletion of putative binding sites
C | each spectrum is classified as either non-random (all three criteria met) or random (0, 1, or 2 criteria met)

## 2.2 Detailed analysis

### 2.2.1 Non-random

Motifs with non-random enrichment pattern (3 out of 3 criteria met)

#### 2.2.1.1 TIA1 (M075_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.744 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.905 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 7e-07 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.1.2 RALY (M150_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.735 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.862 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 3.4e-06 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.1.3 ELAVL1, ELAVL3 (M232_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.709 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.793 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.4e-06 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.1.4 CPEB3, CPEB2 (M012_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.697 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.704 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.2e-06 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

### 2.2.2 Possibly non-random

Motifs with possibly non-random enrichment pattern (2 out of 3 criteria met)

#### 2.2.2.1 ELAVL1, ELAVL3 (M108_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.739 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.741 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.2.2 CPEB3, CPEB4 (M149_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.714 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.793 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.93e-05 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.3 HNRNPC (M025_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.709 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.784 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 6.52e-05 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.4 HNRNPCL1 (M158_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.709 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.784 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 3.01e-05 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.5 ELAVL2 (783_7972035)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.696 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.636 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2.68e-05 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.6 SF3B4 (M201_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.691 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.764 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 7.02e-05 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.7 ELAVL3 (M124_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.54 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.709 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 8.4e-06 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.8 KHDRBS3 (147_19457263)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.497 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.57 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0017996 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

### 2.2.3 Random

Motifs with random enrichment pattern

#### 2.2.3.1 ELAVL1, ELAVL3 (M031_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.724 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.71 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.78e-05 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.2 TIA1 (M156_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.706 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.776 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.19e-05 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.3 U2AF2 (M077_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.705 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.739 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 6.4e-06 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.4 ELAVL2 (784_7972035)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.69 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.655 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0001211 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.5 ELAVL1, ELAVL3 (M127_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.685 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.647 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 6.1e-06 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.6 ELAVL2 (782_8497264)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.636 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.609 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0008672 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.7 ELAVL1, ELAVL3 (M112_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.583 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.59 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.000268 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.8 RBM41 (M051_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.57 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.63 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0015997 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.9 hnRNPK (M026_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.506 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.837 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0145971 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.10 PCBP4, PCBP1, PCBP3 (M177_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.5 | \(\geq 0.4\)
polynomial degree | 3 | \(\geq 1\)
slope | -0.485 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0317936 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.11 PABPC5 (M162_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.494 | \(\geq 0.4\)
polynomial degree | 3 | \(\geq 1\)
slope | 0.42 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0077984 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.12 CELF3 (M229_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.474 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.386 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1107778 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.13 ZFP36 (951_12324455)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.468 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.478 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0091982 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.14 CELF3, BRUNOL5 (M157_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.454 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.373 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0465907 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.15 PCBP4, PCBP3 (M211_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.446 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.528 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0411918 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.16 SRSF1 (M106_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.445 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.549 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0027994 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.17 PCBP4, PCBP3, PCBP2 (M043_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.434 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.621 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0183963 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.18 KHDRBS1 (M160_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.432 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.423 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0155969 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.19 PTBP1, PTBP2, ROD1 (M227_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.422 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.467 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0333933 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.20 PTBP1 (1171_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.414 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.384 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0183963 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.21 ZCRB1 (M085_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.405 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.581 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0545891 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.22 PABPC4, PABPC1L, ENSG00000250177 (M042_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.391 | \(\geq 0.4\)
polynomial degree | 2 | \(\geq 1\)
slope | 0.296 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0157968 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.23 SFRS1 (952_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.388 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.513 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.175165 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.24 SRSF9 (M065_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.386 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.483 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1785643 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.25 CPEB3 (M120_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.38 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.401 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1071786 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.26 HNRNPR, SYNCRIP (M236_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.378 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.381 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0353929 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.27 PCBP4, PCBP3 (M207_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.365 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.427 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0055989 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.28 MSI1, MSI2 (M040_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.365 | \(\geq 0.4\)
polynomial degree | 3 | \(\geq 1\)
slope | 0.544 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0011998 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.29 MSI1, MSI2 (M167_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.365 | \(\geq 0.4\)
polynomial degree | 3 | \(\geq 1\)
slope | 0.544 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0033993 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.30 HNRNPR, SYNCRIP (M243_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.364 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.402 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0001408 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.31 CELF3 (M079_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.362 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.496 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0043991 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.32 SFPQ, PSPC1 (M168_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.342 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.549 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0771846 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.33 FXR2 (M020_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.339 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.844 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.005199 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.34 SRSF12, Fusip1, BX511012.1 (M087_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.334 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.45 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0589882 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.35 SRSF12, Fusip1, BX511012.1 (M086_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.324 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.556 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0015997 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.36 ZRANB2 (1285_19304800)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.318 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.577 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1845631 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.37 KHDRBS3 (1216_19457263)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.314 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.476 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0207958 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.38 NOVA2 (680_9789075)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.308 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.513 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2905419 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.39 NOVA2 (682_10811881)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.295 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.577 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0559888 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.40 RBM5 (M145_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.289 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.515 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2683463 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.41 FMR1 (M016_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.274 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.589 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2973405 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.42 RBM5 (M053_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.274 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.353 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0067986 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.43 ENOX1, ENOX2 (M140_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.27 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.514 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4267147 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.44 LIN28A, LIN28B (M153_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.261 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.579 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0833833 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.45 A1CF (M001_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.251 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.46 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1407718 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.46 DAZAP1 (M013_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.251 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.5 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0867826 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.47 SFRS1 (242_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.247 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.429 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3913217 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.48 MATR3 (M036_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.24 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.443 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4523095 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.49 SAMD4A, SAMD4B (M061_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.236 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.56 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0171966 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.50 CSDA (M260_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.228 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.638 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2239552 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.51 ANKHD1, ANKRD17, ENSG00000249536 (M002_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.605079 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.52 BRUNOL4, CELF3 (M004_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2007598 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.53 RBFOX2, RBFOX3 (M017_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8216357 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.54 SRSF12, Fusip1, BX511012.1 (M019_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4875025 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.55 G3BP2 (M021_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.259948 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.56 HNRNPA1, HNRNPA3, ENSG00000215492, ENSG00000231942 (M022_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4615077 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.57 HNRNPA1L2, HNRNPA3, ENSG00000215492, ENSG00000231942 (M023_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2893421 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.58 HNRNPA2B1, HNRNPA3, ENSG00000215492 (M024_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1495701 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.59 HNRNPL, ENSG00000215042 (M027_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8006399 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.60 IGF2BP2 (M032_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4247151 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.61 KHDRBS3 (M033_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3575285 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.62 LIN28A, LIN28B (M035_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1159768 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.63 MBNL3, MBNL2, MBNL1 (M037_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5546891 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.64 PPRC1 (M044_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3543291 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.65 QKI (M046_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5644871 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.66 RBM28 (M047_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0355929 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.67 CIRBP, RBM3 (M048_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2191562 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.68 RBM38 (M049_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.7914417 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.69 RBM4B, RBM4, RBM4 (M050_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2065587 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.70 RBM46, RBM47 (M052_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.224755 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.71 RBM8A (M054_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5884823 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.72 RBMS2, RBMS3, ENSG00000213250 (M055_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0002648 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.73 SRSF3 (M056_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3629274 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.74 SART3 (M062_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0021996 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.75 SNRNP70 (M068_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0293941 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.76 SNRPA, SNRPB2 (M069_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.44991 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.77 SRSF2, ENSG00000180771 (M070_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0021996 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.78 SRSF7 (M071_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0909818 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.79 SRSF9 (M072_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4467107 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.80 STAR-PAP (M073_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.7592482 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.81 TARDBP (M074_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9962008 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.82 CSDA, YB-1 (M081_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4009198 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.83 YBX2, CSDA (M082_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4389122 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.84 ZC3H10 (M083_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5046991 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.85 SRSF12, Fusip1, BX511012.1 (M088_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8360328 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.86 HNRNPL, ENSG00000215042 (M089_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3209358 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.87 SRSF1 (M102_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2127574 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.88 SRSF1 (M103_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2091582 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.89 SRSF1 (M104_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.104779 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.90 SRSF1 (M105_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0707858 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.91 RBM4B, RBM4, RBM4 (M109_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1413717 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.92 CSDA, YB-1 (M111_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.7864427 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.93 RBFOX2, RBFOX3 (M118_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5524895 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.94 SRSF3 (M121_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9888022 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.95 MEX3C, MEX3D, MEX3B (M122_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2863427 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.96 SRSF4, SRSF6 (M126_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1573685 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.97 SNRPB2 (M136_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6662667 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.98 ESRP2, ESRP1 (M141_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.09978 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.99 RBM42 (M142_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5060988 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.100 RBMS2, RBMS1, ENSG00000213250 (M143_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3863227 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.101 PABPC1L, PABPC3 (M144_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.10018 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.102 PABPC1, PABPC1L, ENSG00000250177 (M146_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0021996 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.103 CNOT4 (M147_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2953409 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.104 PABPN1, PABPN1L (M148_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2025595 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.105 HNRNPH2, HNRNPH1, HNRNPF (M151_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1759648 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.106 FXR1 (M152_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.589882 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.107 SRSF1 (M154_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2905419 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.108 ZNF638 (M155_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.810038 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.109 A2BP1, RBFOX2, RBFOX3 (M159_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8256349 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.110 RBM6 (M161_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0831834 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.111 IGF2BP3 (M163_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6452709 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.112 RBMS2, RBMS3, ENSG00000213250 (M164_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0001351 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.113 hnRNPLL (M169_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9372126 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.114 RBM38 (M170_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6238752 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.115 RBM24, RBM38 (M175_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.7326535 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.116 KHDRBS2 (M176_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1183763 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.117 BRUNOL6, CELF3 (M178_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3459308 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.118 PCBP4, PCBP3 (M188_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6702659 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.119 SF3B4 (M195_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.19996 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.120 SF3B4 (M205_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3493301 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.121 RBM45 (M209_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4057189 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.122 HNRPDL (M210_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8020396 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.123 PTBP1, PTBP2, ROD1 (M228_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5860828 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.124 EIF2S1 (M231_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.825235 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.125 RBM47 (M234_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0245951 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.126 RBM47 (M235_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0259948 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.127 RBM38 (M238_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6908618 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.128 RBM38 (M240_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9094181 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.129 HNRNPR, SYNCRIP (M242_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0353929 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.130 CSDA (M250_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3959208 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.131 CSDA (M254_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3885223 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.132 SF3B4 (M261_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5020996 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.133 SRSF4, SRSF6 (M334_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6446711 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.134 NCL (1004_8676391)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2779444 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.135 SFRS13A (1169_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1167766 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.136 KHDRBS3 (1174_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4045191 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.137 SNRPA (1175_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6576685 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.138 YBX1 (1177_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1331734 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.139 ACO1 (1213_8021254)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1483703 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.140 QKI (1215_16041388)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3739252 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.141 QKI (149_16041388)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6716657 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.142 ZFP36 (221_12324455)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0159968 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.143 HNRNPA1 (23_7510636)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1569686 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.144 SFRS1 (243_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5214957 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.145 SFRS2 (244_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.7404519 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.146 EIF4B (350_8846295)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.329934 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.147 EIF4B (351_8846295)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0717856 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.148 IGF2BP1 (359_12507992)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9242152 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.149 A2BP1 (37_16537540)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.110178 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.150 SNRPA (661_1717938)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.810238 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.151 SNRPA (662_1717938)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5366927 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.152 SNRPA (663_1717938)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5256949 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.153 SFRS7 (790_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8442312 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.154 SFRS2 (791_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3471306 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.155 SNRPA (946_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8712258 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.156 SNRPA (947_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0491902 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.157 SNRPA (948_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2819436 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.158 SNRPA (949_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3207359 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.159 PABPC1 (950_7908267)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4673065 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.160 SFRS2 (953_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0957808 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.161 SFRS7 (954_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1195761 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.162 YTHDC1 (969_20167602)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9998 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

# 3 Download data

Download input data

Download output data

Download full HTML report

Download plots only

# 4 Session info

## 4.1 Loaded motifs

## 4.2 R Session info

    ## R version 3.4.4 (2018-03-15)
    ## Platform: x86_64-pc-linux-gnu (64-bit)
    ## Running under: Ubuntu 16.04.4 LTS
    ##
    ## Matrix products: default
    ## BLAS: /usr/lib/libblas/libblas.so.3.6.0
    ## LAPACK: /usr/lib/lapack/liblapack.so.3.6.0
    ##
    ## locale:
    ##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C
    ##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8
    ##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8
    ##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C
    ##  [9] LC_ADDRESS=C               LC_TELEPHONE=C
    ## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
    ##
    ## attached base packages:
    ## [1] parallel  stats4    methods   stats     graphics  grDevices utils
    ## [8] datasets  base
    ##
    ## other attached packages:
    ##  [1] bindrcpp_0.2.2       transite_0.99.3      DT_0.4
    ##  [4] knitr_1.20           AnnotationDbi_1.40.0 IRanges_2.12.0
    ##  [7] S4Vectors_0.16.0     Biobase_2.38.0       BiocGenerics_0.24.0
    ## [10] rmarkdown_1.9        futile.logger_1.4.3
    ##
    ## loaded via a namespace (and not attached):
    ##  [1] httr_1.3.1
    ##  [2] RMySQL_0.10.15
    ##  [3] bit64_0.9-7
    ##  [4] jsonlite_1.5
    ##  [5] shiny_1.1.0
    ##  [6] assertthat_0.2.0
    ##  [7] blob_1.1.1
    ##  [8] Rsamtools_1.30.0
    ##  [9] GenomeInfoDbData_1.0.0
    ## [10] yaml_2.1.19
    ## [11] progress_1.1.2
    ## [12] lattice_0.20-35
    ## [13] pillar_1.2.3
    ## [14] RSQLite_2.1.1
    ## [15] backports_1.1.2
    ## [16] glue_1.2.0
    ## [17] digest_0.6.15
    ## [18] GenomicRanges_1.30.3
    ## [19] promises_1.0.1
    ## [20] XVector_0.18.0
    ## [21] colorspace_1.3-2
    ## [22] Matrix_1.2-14
    ## [23] htmltools_0.3.6
    ## [24] httpuv_1.4.3
    ## [25] plyr_1.8.4
    ## [26] TxDb.Hsapiens.UCSC.hg38.knownGene_3.4.0
    ## [27] XML_3.98-1.11
    ## [28] pkgconfig_2.0.1
    ## [29] biomaRt_2.34.2
    ## [30] zlibbioc_1.24.0
    ## [31] purrr_0.2.4
    ## [32] xtable_1.8-2
    ## [33] scales_0.5.0
    ## [34] later_0.7.2
    ## [35] BiocParallel_1.12.0
    ## [36] tibble_1.4.2
    ## [37] ggplot2_2.2.1
    ## [38] SummarizedExperiment_1.8.1
    ## [39] GenomicFeatures_1.30.3
    ## [40] TFMPvalue_0.0.8
    ## [41] lazyeval_0.2.1
    ## [42] magrittr_1.5
    ## [43] mime_0.5
    ## [44] memoise_1.1.0
    ## [45] evaluate_0.10.1
    ## [46] tools_3.4.4
    ## [47] prettyunits_1.0.2
    ## [48] org.Hs.eg.db_3.5.0
    ## [49] matrixStats_0.53.1
    ## [50] formatR_1.5
    ## [51] stringr_1.3.1
    ## [52] munsell_0.4.3
    ## [53] DelayedArray_0.4.1
    ## [54] lambda.r_1.2.3
    ## [55] Biostrings_2.46.0
    ## [56] compiler_3.4.4
    ## [57] GenomeInfoDb_1.14.0
    ## [58] rlang_0.2.0
    ## [59] grid_3.4.4
    ## [60] RCurl_1.95-4.10
    ## [61] htmlwidgets_1.2
    ## [62] crosstalk_1.0.0
    ## [63] labeling_0.3
    ## [64] bitops_1.0-6
    ## [65] gtable_0.2.0
    ## [66] DBI_1.0.0
    ## [67] R6_2.2.2
    ## [68] GenomicAlignments_1.14.2
    ## [69] gridExtra_2.3
    ## [70] rtracklayer_1.38.3
    ## [71] dplyr_0.7.5
    ## [72] bit_1.1-13
    ## [73] bindr_0.1.1
    ## [74] rprojroot_1.3-2
    ## [75] futile.options_1.0.1
    ## [76] stringi_1.2.2
    ## [77] Rcpp_0.12.17
    ## [78] dbplyr_1.2.1
    ## [79] tidyselect_0.2.4