# ZFP36 overexpression Tuschl

#### icannell@nygenome.org

#### 2018-09-24

# 1 Metadata

## 1.1 Configuration

Analysis approach:

    approach <- "matrix"

Species:

    species <- "human"

Graphical output format:

    graphics.format <- "SVG"

Sequence region:

    sequence.type <- "3UTR"

Number of bins:

    n.bins <- 40

Merge method for duplicate entries:

    merge.method <- "highest.magnitude"

Maximum degree of polynomial model for spectrum evaluation:

    max.model.degree <- 1

P-value adjustment method:

    p.adjust.method <- "BH"

Maxmimum number of binding sites per transcript:

    max.hits <- 5

Motif database:

    motif.db <- "transite"

## 1.2 Sequence data retrieval

- merge rows with duplicate RefSeq identifiers
- retrieve requested sequence regions (3’ UTRs, 5’ UTRs, or mature mRNAs) for each RefSeq identifier using
  - GRCh38/hg38 genome assembly for human platforms
  - GRCm38/mm10 genome assembly for mouse platforms
- draw histogram of length distribution of retrieved sequences
- draw histogram of value distribution of retrieved sequences (“value” column in uploaded file)

The latest genome assembly releases (GRCh38/hg38 for human platforms, GRCm38/mm10 for mouse platforms) are used to retrieve the requested sequence regions for all specified transcripts.

### 1.2.1 Duplicate RefSeq identifier

Number of occurrences per category before merge step:

### 1.2.2 Summary of sequence data

Sequence data retrieval summary:

Property | Value
--- | ---
number of valid RefSeq identifiers | 10991
number of invalid RefSeq identifiers | 20
number of RefSeq identifiers with associated sequence | 10744
species | human
sequence type | 3UTR
platform | custom

Length distribution of retrieved sequences:

### 1.2.3 Value distribution of transcripts

Histogram of the differential expression values (`value` column):

# 2 Matrix-based Spectrum Motif Analysis

Warning: The presented results are speculative and should be used with caution. Especially the link between the RNA-binding protein and its sequence motif (i.e., the PWM) is not well established. It is recommended to interpret the results with the underlying PWMs in mind, instead of only looking at the associated RNA-binding proteins. Sequence motif logos and PWMs of all RNA-binding proteins in the database can be found in the Motif Database section of the Transite website.

Transcripts in bin 1 have smallest value in `value` column, transcripts in bin 40 have greatest value in `value` column.

Binning scheme: 39 bins with 268 transcripts each, last bin with 292 transcripts

## 2.1 Summary

Spectrums that meet the following criteria are considered non-random (and random otherwise):

- adjusted \(R^2 \geq 0.4\)
- local consistency score Monte Carlo sampling \(n > 1000000\)
- at least 10% of bins with significant (\(\alpha = 0.05\)) enrichment or depletion of putative binding sites

Color legend:

spectrum classification: non-random (3 out of 3 criteria met)

spectrum classification: random (2 out of 3 criteria met)

spectrum classification: random (1 out of 3 criteria met)

spectrum classification: random (0 out of 3 criteria met)

Column | Description
--- | ---
ID | unique motif ID
RBPs | RNA-binding proteins associated with this motif
ARS | adjusted \(R^2\)
slope | either slope (if degree 1 polynomial), or coefficient of the linear term (if degree greater than 1); positive slope implies enrichment of putative binding sites in highly ranked transcripts (according to value column), negative slope implies depletion
degree | polynomial degree
p-value | adjusted p-value of local consistency score
* | number of bins with significant (\(\alpha = 0.05\)) enrichment or depletion of putative binding sites
** | number of bins with highly significant (\(\alpha = 0.01\)) enrichment or depletion of putative binding sites
*** | number of bins with extremely significant (\(\alpha = 0.001\)) enrichment or depletion of putative binding sites
C | each spectrum is classified as either non-random (all three criteria met) or random (0, 1, or 2 criteria met)

## 2.2 Detailed analysis

### 2.2.1 Non-random

Motifs with non-random enrichment pattern (3 out of 3 criteria met)

#### 2.2.1.1 ZFP36 (951_12324455)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.95 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.913 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 30 | \(\geq 4\)

#### 2.2.1.2 RBM41 (M051_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.931 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.768 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 28 | \(\geq 4\)

#### 2.2.1.3 A1CF (M001_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.93 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -2.099 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 29 | \(\geq 4\)

#### 2.2.1.4 RBMS2, RBMS3, ENSG00000213250 (M164_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.927 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -2.219 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 26 | \(\geq 4\)

#### 2.2.1.5 RBMS2, RBMS3, ENSG00000213250 (M055_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.916 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -2.19 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 26 | \(\geq 4\)

#### 2.2.1.6 KHDRBS3 (147_19457263)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.908 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.454 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 26 | \(\geq 4\)

#### 2.2.1.7 ELAVL1, ELAVL3 (M112_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.89 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.123 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 27 | \(\geq 4\)

#### 2.2.1.8 PCBP4, PCBP3 (M207_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.878 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.472 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 23 | \(\geq 4\)

#### 2.2.1.9 PCBP4, PCBP3, PCBP2 (M043_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.875 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.487 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 30 | \(\geq 4\)

#### 2.2.1.10 SRSF9 (M065_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.875 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.497 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 23 | \(\geq 4\)

#### 2.2.1.11 SRSF1 (M105_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.872 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.824 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 26 | \(\geq 4\)

#### 2.2.1.12 KHDRBS3 (1216_19457263)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.869 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.815 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 25 | \(\geq 4\)

#### 2.2.1.13 ELAVL2 (783_7972035)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.869 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.869 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 18 | \(\geq 4\)

#### 2.2.1.14 SRSF1 (M104_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.867 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.813 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 26 | \(\geq 4\)

#### 2.2.1.15 PTBP1 (1171_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.866 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.86 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 20 | \(\geq 4\)

#### 2.2.1.16 SRSF1 (M154_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.861 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.693 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 21 | \(\geq 4\)

#### 2.2.1.17 KHDRBS1 (M160_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.861 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.099 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 22 | \(\geq 4\)

#### 2.2.1.18 RBMS2, RBMS1, ENSG00000213250 (M143_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.861 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.954 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 21 | \(\geq 4\)

#### 2.2.1.19 ELAVL1, ELAVL3 (M127_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.856 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.998 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 23 | \(\geq 4\)

#### 2.2.1.20 ELAVL1, ELAVL3 (M108_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.852 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.161 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 23 | \(\geq 4\)

#### 2.2.1.21 ELAVL2 (784_7972035)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.851 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.813 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 16 | \(\geq 4\)

#### 2.2.1.22 CELF3 (M079_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.85 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.071 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 12 | \(\geq 4\)

#### 2.2.1.23 SRSF1 (M102_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.848 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.525 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2e-07 | \(< 0.000005\)
number of significant bins | 22 | \(\geq 4\)

#### 2.2.1.24 SRSF1 (M103_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.848 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.525 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2e-07 | \(< 0.000005\)
number of significant bins | 21 | \(\geq 4\)

#### 2.2.1.25 SRSF4, SRSF6 (M126_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.844 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.082 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 28 | \(\geq 4\)

#### 2.2.1.26 hnRNPK (M026_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.838 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.155 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 22 | \(\geq 4\)

#### 2.2.1.27 ZCRB1 (M085_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.838 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.54 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 20 | \(\geq 4\)

#### 2.2.1.28 ELAVL2 (782_8497264)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.838 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.717 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 14 | \(\geq 4\)

#### 2.2.1.29 PABPC5 (M162_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.836 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.179 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 24 | \(\geq 4\)

#### 2.2.1.30 SFRS1 (952_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.819 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.153 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2.4e-06 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.1.31 ESRP2, ESRP1 (M141_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.816 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.149 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 17 | \(\geq 4\)

#### 2.2.1.32 RBM5 (M145_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.816 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.662 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 21 | \(\geq 4\)

#### 2.2.1.33 HNRNPR, SYNCRIP (M243_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.805 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.86 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 21 | \(\geq 4\)

#### 2.2.1.34 SRSF2, ENSG00000180771 (M070_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.8 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.898 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 10 | \(\geq 4\)

#### 2.2.1.35 SF3B4 (M201_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.792 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.774 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 17 | \(\geq 4\)

#### 2.2.1.36 LIN28A, LIN28B (M153_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.79 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.798 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 17 | \(\geq 4\)

#### 2.2.1.37 ELAVL1, ELAVL3 (M031_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.789 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.703 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 13 | \(\geq 4\)

#### 2.2.1.38 CPEB3, CPEB2 (M012_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.789 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.775 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 3.2e-06 | \(< 0.000005\)
number of significant bins | 15 | \(\geq 4\)

#### 2.2.1.39 FXR2 (M020_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.779 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.049 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 19 | \(\geq 4\)

#### 2.2.1.40 CSDA (M260_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.77 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.078 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 13 | \(\geq 4\)

#### 2.2.1.41 PCBP4, PCBP1, PCBP3 (M177_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.766 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.156 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 8 | \(\geq 4\)

#### 2.2.1.42 PTBP1, PTBP2, ROD1 (M227_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.765 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.536 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 7 | \(\geq 4\)

#### 2.2.1.43 SNRPA (947_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.763 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.088 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2e-07 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.1.44 RALY (M150_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.759 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.683 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.3e-06 | \(< 0.000005\)
number of significant bins | 11 | \(\geq 4\)

#### 2.2.1.45 FMR1 (M016_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.758 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.277 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.9e-06 | \(< 0.000005\)
number of significant bins | 15 | \(\geq 4\)

#### 2.2.1.46 SRSF1 (M106_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.758 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.033 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.5e-06 | \(< 0.000005\)
number of significant bins | 15 | \(\geq 4\)

#### 2.2.1.47 PCBP4, PCBP3 (M211_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.757 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.873 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.7e-06 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.1.48 NOVA2 (680_9789075)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.755 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.069 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 3e-07 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.1.49 TIA1 (M156_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.755 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.642 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 3e-06 | \(< 0.000005\)
number of significant bins | 12 | \(\geq 4\)

#### 2.2.1.50 HNRNPC (M025_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.753 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.662 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2e-07 | \(< 0.000005\)
number of significant bins | 14 | \(\geq 4\)

#### 2.2.1.51 HNRNPCL1 (M158_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.753 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.662 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4e-07 | \(< 0.000005\)
number of significant bins | 12 | \(\geq 4\)

#### 2.2.1.52 NOVA2 (682_10811881)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.746 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.474 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2e-07 | \(< 0.000005\)
number of significant bins | 13 | \(\geq 4\)

#### 2.2.1.53 QKI (1215_16041388)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.744 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.143 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 7 | \(\geq 4\)

#### 2.2.1.54 CPEB3, CPEB4 (M149_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.74 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.627 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 6e-07 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.1.55 ZC3H10 (M083_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.722 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.556 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 10 | \(\geq 4\)

#### 2.2.1.56 HNRNPR, SYNCRIP (M236_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.722 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.833 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 14 | \(\geq 4\)

#### 2.2.1.57 PABPC1L, PABPC3 (M144_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.719 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.643 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.6e-06 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.1.58 QKI (149_16041388)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.717 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.344 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.9e-06 | \(< 0.000005\)
number of significant bins | 7 | \(\geq 4\)

#### 2.2.1.59 RBM4B, RBM4, RBM4 (M109_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.712 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.568 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.1.60 SNRPA (948_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.705 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.273 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2e-07 | \(< 0.000005\)
number of significant bins | 13 | \(\geq 4\)

#### 2.2.1.61 IGF2BP2 (M032_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.655 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.748 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.2e-06 | \(< 0.000005\)
number of significant bins | 10 | \(\geq 4\)

#### 2.2.1.62 BRUNOL6, CELF3 (M178_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.649 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.706 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 5e-06 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.1.63 SART3 (M062_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.642 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.521 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2e-06 | \(< 0.000005\)
number of significant bins | 7 | \(\geq 4\)

#### 2.2.1.64 PTBP1, PTBP2, ROD1 (M228_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: non-random (3 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.435 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.378 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 5.9e-06 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

### 2.2.2 Possibly non-random

Motifs with possibly non-random enrichment pattern (2 out of 3 criteria met)

#### 2.2.2.1 KHDRBS3 (1174_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.916 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.917 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.2 RBM46, RBM47 (M052_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.871 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.372 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.3 HNRNPH2, HNRNPH1, HNRNPF (M151_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.85 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.815 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.4 ELAVL3 (M124_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.833 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.118 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.5 SAMD4A, SAMD4B (M061_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.811 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.551 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.6 SRSF12, Fusip1, BX511012.1 (M086_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.778 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.765 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 3.55e-05 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

#### 2.2.2.7 SFRS2 (953_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.771 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.811 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 6.9e-06 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.2.8 SFRS1 (242_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.762 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.857 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 8e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.9 SRSF9 (M072_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.747 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.688 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.06e-05 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

#### 2.2.2.10 TIA1 (M075_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.745 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.666 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.11 U2AF2 (M077_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.738 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.611 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 7.5e-06 | \(< 0.000005\)
number of significant bins | 12 | \(\geq 4\)

#### 2.2.2.12 ACO1 (1213_8021254)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.733 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.028 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 7.7e-06 | \(< 0.000005\)
number of significant bins | 10 | \(\geq 4\)

#### 2.2.2.13 ELAVL1, ELAVL3 (M232_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.71 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.596 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 6.6e-06 | \(< 0.000005\)
number of significant bins | 7 | \(\geq 4\)

#### 2.2.2.14 MEX3C, MEX3D, MEX3B (M122_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.708 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.89 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 8.1e-06 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.2.15 ZRANB2 (1285_19304800)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.702 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.056 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0008537 | \(< 0.000005\)
number of significant bins | 6 | \(\geq 4\)

#### 2.2.2.16 YBX1 (1177_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.7 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.575 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1e-07 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.17 KHDRBS2 (M176_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.698 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.72 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0005723 | \(< 0.000005\)
number of significant bins | 11 | \(\geq 4\)

#### 2.2.2.18 SRSF4, SRSF6 (M334_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.689 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.597 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0005107 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

#### 2.2.2.19 MATR3 (M036_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.677 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.835 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.15e-05 | \(< 0.000005\)
number of significant bins | 8 | \(\geq 4\)

#### 2.2.2.20 CELF3 (M229_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.677 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.499 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0007696 | \(< 0.000005\)
number of significant bins | 6 | \(\geq 4\)

#### 2.2.2.21 EIF4B (351_8846295)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.669 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.032 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.26e-05 | \(< 0.000005\)
number of significant bins | 11 | \(\geq 4\)

#### 2.2.2.22 CNOT4 (M147_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.666 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.732 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0011998 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

#### 2.2.2.23 PABPC1 (950_7908267)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.648 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.576 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 7.44e-05 | \(< 0.000005\)
number of significant bins | 9 | \(\geq 4\)

#### 2.2.2.24 PABPC1, PABPC1L, ENSG00000250177 (M146_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.642 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.521 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 2.3e-06 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.2.25 PABPC4, PABPC1L, ENSG00000250177 (M042_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.609 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.54 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.74e-05 | \(< 0.000005\)
number of significant bins | 7 | \(\geq 4\)

#### 2.2.2.26 RBM38 (M240_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.591 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.659 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0003754 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

#### 2.2.2.27 RBM42 (M142_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.59 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.343 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 5.65e-05 | \(< 0.000005\)
number of significant bins | 8 | \(\geq 4\)

#### 2.2.2.28 NCL (1004_8676391)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.53 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.973 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0021996 | \(< 0.000005\)
number of significant bins | 6 | \(\geq 4\)

#### 2.2.2.29 ENOX1, ENOX2 (M140_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.505 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.718 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0019996 | \(< 0.000005\)
number of significant bins | 6 | \(\geq 4\)

#### 2.2.2.30 HNRPDL (M210_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.504 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.86 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0001713 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.31 STAR-PAP (M073_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.504 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.117 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0011998 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

#### 2.2.2.32 DAZAP1 (M013_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.49 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.861 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0161968 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.33 PCBP4, PCBP3 (M188_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.474 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.382 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0719856 | \(< 0.000005\)
number of significant bins | 5 | \(\geq 4\)

#### 2.2.2.34 CPEB3 (M120_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.451 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.409 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0083983 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.2.35 RBM47 (M234_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (2 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.422 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.641 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 4.99e-05 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

### 2.2.3 Random

Motifs with random enrichment pattern

#### 2.2.3.1 HNRNPR, SYNCRIP (M242_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.757 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -1.087 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.22e-05 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.2 SRSF12, Fusip1, BX511012.1 (M087_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.609 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.436 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0011998 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.3 ZFP36 (221_12324455)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.597 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.513 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 6.03e-05 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.4 MSI1, MSI2 (M040_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.591 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.866 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0002081 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.5 MSI1, MSI2 (M167_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.591 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.866 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0004004 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.6 RBM5 (M053_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.581 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.609 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 1.6e-05 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.7 LIN28A, LIN28B (M035_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.544 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.458 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0195961 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.8 KHDRBS3 (M033_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.543 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.628 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 8e-06 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.9 RBM38 (M049_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.54 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.514 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0013997 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.10 IGF2BP3 (M163_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.518 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.454 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 7.88e-05 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.11 MBNL3, MBNL2, MBNL1 (M037_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.496 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.69 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0011998 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.12 FXR1 (M152_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.495 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.819 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0035993 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.13 RBM4B, RBM4, RBM4 (M050_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.455 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 2.019 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.014797 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.14 RBM38 (M238_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.439 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.497 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0079984 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.15 CSDA, YB-1 (M081_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.422 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.51 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0029994 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.16 CSDA (M250_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.42 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.511 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0015997 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.17 CSDA (M254_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.42 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.511 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0015997 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.18 SF3B4 (M195_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.42 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.514 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0107978 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.19 EIF4B (350_8846295)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.4 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.482 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.035193 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.20 QKI (M046_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.383 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.724 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0839832 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.21 SFPQ, PSPC1 (M168_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.378 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.457 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1005799 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.22 IGF2BP1 (359_12507992)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.375 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.666 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0181964 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.23 TARDBP (M074_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.361 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.422 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0057988 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.24 SF3B4 (M205_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.359 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.366 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1233753 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.25 SNRPA (949_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.355 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.523 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1013797 | \(< 0.000005\)
number of significant bins | 3 | \(\geq 4\)

#### 2.2.3.26 YBX2, CSDA (M082_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.354 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.647 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0623875 | \(< 0.000005\)
number of significant bins | 4 | \(\geq 4\)

#### 2.2.3.27 RBM47 (M235_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (1 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.344 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.668 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0005742 | \(< 0.000005\)
number of significant bins | 6 | \(\geq 4\)

#### 2.2.3.28 RBM38 (M170_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.318 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.301 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0419916 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.29 RBM45 (M209_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.279 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 1.332 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0671866 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.30 CSDA, YB-1 (M111_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.267 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.424 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2723455 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.31 RBM28 (M047_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.262 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.525 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4127175 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.32 SRSF12, Fusip1, BX511012.1 (M019_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.259 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.243 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0783843 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.33 SNRPA (946_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.251 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.293 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0167966 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.34 CELF3, BRUNOL5 (M157_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.251 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | -0.203 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0687862 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.35 SF3B4 (M261_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0.248 | \(\geq 0.4\)
polynomial degree | 1 | \(\geq 1\)
slope | 0.253 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.074785 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.36 ANKHD1, ANKRD17, ENSG00000249536 (M002_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.7968406 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.37 BRUNOL4, CELF3 (M004_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6262747 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.38 RBFOX2, RBFOX3 (M017_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4381124 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.39 G3BP2 (M021_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1435713 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.40 HNRNPA1, HNRNPA3, ENSG00000215492, ENSG00000231942 (M022_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9322136 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.41 HNRNPA1L2, HNRNPA3, ENSG00000215492, ENSG00000231942 (M023_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6886623 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.42 HNRNPA2B1, HNRNPA3, ENSG00000215492 (M024_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0929814 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.43 HNRNPL, ENSG00000215042 (M027_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3215357 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.44 PPRC1 (M044_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3593281 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.45 CIRBP, RBM3 (M048_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3733253 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.46 RBM8A (M054_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2635473 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.47 SRSF3 (M056_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6116777 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.48 SNRNP70 (M068_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5088982 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.49 SNRPA, SNRPB2 (M069_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2371526 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.50 SRSF7 (M071_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2171566 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.51 SRSF12, Fusip1, BX511012.1 (M088_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2637473 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.52 HNRNPL, ENSG00000215042 (M089_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0315937 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.53 RBFOX2, RBFOX3 (M118_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9930014 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.54 SRSF3 (M121_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4117177 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.55 SNRPB2 (M136_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1435713 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.56 PABPN1, PABPN1L (M148_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0743851 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.57 ZNF638 (M155_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.5708858 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.58 A2BP1, RBFOX2, RBFOX3 (M159_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.4207159 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.59 RBM6 (M161_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.169966 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.60 hnRNPLL (M169_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1881624 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.61 RBM24, RBM38 (M175_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.1857628 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.62 EIF2S1 (M231_0.6)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.420116 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.63 SFRS13A (1169_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.8026395 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.64 SNRPA (1175_19561594)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2959408 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.65 HNRNPA1 (23_7510636)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0991802 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.66 SFRS1 (243_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2633473 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.67 SFRS2 (244_7543047)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9230154 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.68 A2BP1 (37_16537540)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9868026 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.69 SNRPA (661_1717938)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.2709458 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.70 SNRPA (662_1717938)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6014797 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.71 SNRPA (663_1717938)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.6358728 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.72 SFRS7 (790_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.3869226 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

#### 2.2.3.73 SFRS2 (791_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.029794 | \(< 0.000005\)
number of significant bins | 1 | \(\geq 4\)

#### 2.2.3.74 SFRS7 (954_10094314)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.0241952 | \(< 0.000005\)
number of significant bins | 2 | \(\geq 4\)

#### 2.2.3.75 YTHDC1 (969_20167602)

Spectrum plot with polynomial regression:

Classification:

spectrum classification: random (0 out of 3 criteria met)

Property | Value | Threshold
--- | --- | ---
adjusted \(R^2\) | 0 | \(\geq 0.4\)
polynomial degree | 0 | \(\geq 1\)
slope | 0 | \(\neq 0\)
unadjusted p-value estimate of consistency score | 0.9998 | \(< 0.000005\)
number of significant bins | 0 | \(\geq 4\)

# 3 Download data

Download input data

Download output data

Download full HTML report

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# 4 Session info

## 4.1 Loaded motifs

## 4.2 R Session info

    ## R version 3.5.1 (2018-07-02)
    ## Platform: x86_64-pc-linux-gnu (64-bit)
    ## Running under: Ubuntu 16.04.5 LTS
    ##
    ## Matrix products: default
    ## BLAS: /usr/lib/libblas/libblas.so.3.6.0
    ## LAPACK: /usr/lib/lapack/liblapack.so.3.6.0
    ##
    ## locale:
    ##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C
    ##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8
    ##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8
    ##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C
    ##  [9] LC_ADDRESS=C               LC_TELEPHONE=C
    ## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
    ##
    ## attached base packages:
    ## [1] parallel  stats4    stats     graphics  grDevices utils     datasets
    ## [8] methods   base
    ##
    ## other attached packages:
    ##  [1] bindrcpp_0.2.2       transite_0.99.3      DT_0.4
    ##  [4] knitr_1.20           AnnotationDbi_1.42.1 IRanges_2.14.11
    ##  [7] S4Vectors_0.18.3     Biobase_2.40.0       BiocGenerics_0.26.0
    ## [10] rmarkdown_1.10       futile.logger_1.4.3
    ##
    ## loaded via a namespace (and not attached):
    ##  [1] httr_1.3.1
    ##  [2] bit64_0.9-7
    ##  [3] jsonlite_1.5
    ##  [4] shiny_1.1.0
    ##  [5] assertthat_0.2.0
    ##  [6] blob_1.1.1
    ##  [7] Rsamtools_1.32.3
    ##  [8] GenomeInfoDbData_1.1.0
    ##  [9] yaml_2.2.0
    ## [10] progress_1.2.0
    ## [11] lattice_0.20-35
    ## [12] pillar_1.3.0
    ## [13] RSQLite_2.1.1
    ## [14] backports_1.1.2
    ## [15] glue_1.3.0
    ## [16] digest_0.6.17
    ## [17] GenomicRanges_1.32.6
    ## [18] promises_1.0.1
    ## [19] XVector_0.20.0
    ## [20] colorspace_1.3-2
    ## [21] Matrix_1.2-14
    ## [22] htmltools_0.3.6
    ## [23] httpuv_1.4.5
    ## [24] plyr_1.8.4
    ## [25] TxDb.Hsapiens.UCSC.hg38.knownGene_3.4.0
    ## [26] XML_3.98-1.16
    ## [27] pkgconfig_2.0.2
    ## [28] biomaRt_2.36.1
    ## [29] zlibbioc_1.26.0
    ## [30] purrr_0.2.5
    ## [31] xtable_1.8-3
    ## [32] scales_1.0.0
    ## [33] later_0.7.4
    ## [34] BiocParallel_1.14.2
    ## [35] tibble_1.4.2
    ## [36] ggplot2_3.0.0
    ## [37] SummarizedExperiment_1.10.1
    ## [38] GenomicFeatures_1.32.2
    ## [39] TFMPvalue_0.0.8
    ## [40] lazyeval_0.2.1
    ## [41] magrittr_1.5
    ## [42] crayon_1.3.4
    ## [43] mime_0.5
    ## [44] memoise_1.1.0
    ## [45] evaluate_0.11
    ## [46] prettyunits_1.0.2
    ## [47] tools_3.5.1
    ## [48] hms_0.4.2
    ## [49] org.Hs.eg.db_3.6.0
    ## [50] matrixStats_0.54.0
    ## [51] formatR_1.5
    ## [52] stringr_1.3.1
    ## [53] munsell_0.5.0
    ## [54] DelayedArray_0.6.6
    ## [55] lambda.r_1.2.3
    ## [56] Biostrings_2.48.0
    ## [57] compiler_3.5.1
    ## [58] GenomeInfoDb_1.16.0
    ## [59] rlang_0.2.2
    ## [60] grid_3.5.1
    ## [61] RCurl_1.95-4.11
    ## [62] htmlwidgets_1.2
    ## [63] crosstalk_1.0.0
    ## [64] labeling_0.3
    ## [65] bitops_1.0-6
    ## [66] gtable_0.2.0
    ## [67] DBI_1.0.0
    ## [68] R6_2.2.2
    ## [69] GenomicAlignments_1.16.0
    ## [70] gridExtra_2.3
    ## [71] rtracklayer_1.40.6
    ## [72] dplyr_0.7.6
    ## [73] bit_1.1-14
    ## [74] bindr_0.1.1
    ## [75] rprojroot_1.3-2
    ## [76] futile.options_1.0.1
    ## [77] stringi_1.2.4
    ## [78] Rcpp_0.12.18
    ## [79] dbplyr_1.2.2
    ## [80] tidyselect_0.2.4